Electrolyzed-reduced water confers increased resistance to environmental stresses
by Sang-Kyu Park, Seul-Ki Park, A-Reum Yu, Jum-Ji Kim, Mi-Young Lee
Abstract:
Electrolysis of water produces reduced water at the cathode and oxidized water at the anode. Electrolyzed-reduced water (ERW) has an extremely negative oxidation-reduction potential. ERW scavenges cellular reactive oxygen species (ROS) and suppresses single-strand breaks of plasmid DNA in bacteria. Here, we examined the effect of ERW on resistance to oxidative stress both in vitro and in vivo. Oxidative DNA damage in human lymphocytes was significantly alleviated by ERW by reducing cellular ROS levels. Caenorhabditis elegans grown in media prepared with ERW had increased resistance to oxidative stress caused by paraquat. We observed a significant effect of ERW on response to other stressors, including heat shock and UV-irradiation in C. elegans. These data indicate that the powerful anti-oxidant activity of ERW is due to its radical-scavenging activity and show, for the first time, that ERW could increase thermotolerance and resistance to UV-irradiation. These results suggest that ERW aids resistance to various environmental stresses.
Read more:
https://doi.org/10.1007/s13273-012-0029-1
Related Articles:
Objective: Molecular hydrogen (H2) has shown therapeutic potential in several oxidative stress-related conditions in humans, is well-tolerated, and is easily administered via inhalation.The aim of this preclinical in vivo study was to investigate whether impulse noise trauma can be prevented…
Related studies have shown that chromium (Cr) is toxic to cells, and hydrogen can protect cells by regulating endoplasmic reticulum (ER) stress and autophagy. However, there are few reports on the protective effects of hydrogen on heavy metal-induced cell damage….
Oxidative stress plays a pathological role in pulmonary hypoplasia and pulmonary hypertension in congenital diaphragmatic hernia (CDH). This study investigated the effect of molecular hydrogen (H2), an antioxidant, on CDH pathology induced by nitrofen. Sprague-Dawley rats were divided into three…
In recent years, studies investigating the protective effect of hydrogen-rich water (HRW) against different diseases and the toxicity of some substances have attracted increasing attention. Here, we assessed the effects of hydrogen-rich water on different nickel-induced toxic responses (reactive oxygen…
The toxic effects of mercury in earthworms and the potential alleviation effect of hydrogen-rich water (HRW) using ATR-FTIR and LC-MS analysis methods were investigated. Different concentrations of mercury chloride (H1: 5 µg/mL, H2: 10 µg/mL, H3: 20 µg/mL, H4: 40…
Oxidative stress (OS) is one of the causative factors in the pathogenesis of various neurodegenerative diseases, including Alzheimer’s disease (AD) and cognitive dysfunction. In the present study, we investigated the effects of hydrogen (H2) gas inhalation in trimethyltin (TMT)-induced neurotoxicity…






0 Comments