The Suppressive Effect of Electrolyzed Reduced Water on Lipid Peroxidation
by Sanetaka Shirahata, Takeki Hamasaki, S. Kabayama, K. Otsubo, K. Teruya, S. Morisawa, Y. Katakura, Y. Sugihara
Abstract:
We examined the suppressive effect on lipid peroxidation of electrolyzed reduced water (ERW), which exhibited reactive oxygen species (ROS)-scavenging activity in vitro and in cultured cells. The oxidation of linoleic acid by 2, 2’-azobis (2-amidinopropane) hydrochloride (AAPH) was suppressed by ERW in vitro. ERW also suppressed the lipid peroxidation in cell membrane of mouse lymphoblast YAC-1 cells. Transparent electron microscopic analysis revealed that platinum in ERW existed as a colloidal form of nm size. Concentrated ERW suppressed the lipid peroxidation in a manner dependent upon the concentration of platinum nanocolloids, and chemical synthesized platinum nanocolloids exhibited a similar suppressive effect on lipid peroxidation to that of ERW, suggesting that platinum nanocolloids contained in ERW were reducing agents to suppress the lipid peroxidation.
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https://doi.org/10.1007/978-94-017-0726-8_66
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