Electrochemically Reduced Water: Modification of the Incubation Medium and Oxidative Activity
by A.G. Pogorelov, M.A. Pogorelova, V.N. Pogorelova
Abstract:
It has been shown that Dulbecco’s incubation medium prepared with electrochemically reduced water compensates for oxidative stress induced by hydrogen peroxide addition (H2O2, 0.2 mM) to the incubation medium. The incubation medium modified in this way does not affect the H2O2 induced apoptosis in an early mouse embryo. The embryonic cell in the experimental model of apoptosis shows the presence of characteristic morphological changes and decreased cell volume. These apoptosis-related changes were detected using laser-scanning microtomography.
Read more:
https://doi.org/10.1134/S0006350918010153
Related Articles:
Intervertebral disc degeneration (IVDD) is a degenerative disease characterized by lower-back pain, causing disability globally. Antioxidant therapy is currently considered one of the most promising strategies for IVDD treatment, given the crucial role of reactive oxygen species (ROS) in IVDD…
Aim: To analyze the effectiveness and safety of hydrogen inhalation (HI) therapy as an adjunct treatment in Chinese type 2 diabetes mellitus (T2DM) patients in a real-life clinical setting. Methods: This observational, non-interventional, retrospective, double-arm, 6-month clinical study included T2DM…
The anti-inflammatory and anti-apoptotic effects of molecular hydrogen, delivered as hydrogen-rich saline (HRS), on spinal cord injury was investigated. Four-month-old male Sprague Dawley rats (n = 24) were classified into four groups: (1) control-laminectomy only at T7-T10; (2) spinal injury-dura…
As the most important natural antioxidants in plant extracts, polyphenols demonstrate versatile bioactivities and are susceptible to oxidation. The commonly used ultrasonic extraction often causes oxidation reactions involving the formation of free radicals. To minimize the oxidation effects during the…
Background: Premature ovarian failure (POF) is defined as the cessation of ovarian function before the age of 40 years, imposing a significant health burden on patients. However, effective etiological therapy for POF is scarce. Thus, we aimed to explore the…
Hydrogen (H2) is a major biodegradation product of implanted magnesium (Mg) alloys that are commonly used in the healing of bone fractures. Our earlier study showed that H2 can inhibit mouse bone marrow mononuclear cell (BMMC) osteoclastogenesis during the differentiation…
0 Comments